AD: Shocked! The peak value of plasma Aβ42/Aβ40 began to decline 41 years before the deposition of brain Aβ! Alzheimer's diseases: New discovery on plasma Aβ42/Aβ40. AD: Shocked! The peak value of plasma Aβ42/Aβ40 began to decline 41 years before the deposition of brain Aβ! Amyloid β (Aβ) plaque deposition and phosphorylated tau (p-tau) protein tangles are two important pathological features of Alzheimer's disease (AD), and there are many kinds of AD biomarkers derived around them, Knowledge of the longitudinal trajectories of key markers could not only help improve the selection and monitoring of participants in clinical trials, but also help identify those at high risk for neurodegenerative changes and cognitive impairment. Although research on AD biomarkers has increased substantially in recent years, research on longitudinal changes in biomarkers is relatively limited. Studies have shown that the levels of plasma Aβ 42 /Aβ 40 , p-tau181 and glial fibrillary acidic...
After 70 years of age, language ability declines significantly, and more play and activity can delay it!
After 70 years of age, language ability declines significantly, and more play and activity can delay it! 70~74 years old is a turning point in the decline of language ability Playing more and more active can delay the decline of speech function Liu Chuqun, Professor of Jiangxi Normal University Decreased language fluency is an important speech performance of the elderly. Studies have found that the age of 70 to 74 is an important turning point for the decline of verbal fluency, but a positive attitude and a healthy lifestyle can delay the decline of the elderly’s verbal fluency to a certain extent. After 70 years of age, language ability declines significantly Most of the elderly, especially the elderly, have these kinds of expressions: words that have no real meaning are repeated back and forth, lack of information to express, the words are inconsistent with what they think and form a verbal error, and the words cannot be remembered by the mouth (tip of tongue phenomenon), ...