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Showing posts from April, 2021

AD: Shocked! The peak value of plasma Aβ42/Aβ40 began to decline 41 years before the deposition of brain Aβ!

 AD: Shocked! The peak value of plasma Aβ42/Aβ40 began to decline 41 years before the deposition of brain Aβ! Alzheimer's diseases: New discovery on plasma Aβ42/Aβ40.  AD: Shocked! The peak value of plasma Aβ42/Aβ40 began to decline 41 years before the deposition of brain Aβ! Amyloid β (Aβ) plaque deposition and phosphorylated tau (p-tau) protein tangles are two important pathological features of Alzheimer's disease (AD), and there are many kinds of AD biomarkers derived around them, Knowledge of the longitudinal trajectories of key markers could not only help improve the selection and monitoring of participants in clinical trials, but also help identify those at high risk for neurodegenerative changes and cognitive impairment.   Although research on AD biomarkers has increased substantially in recent years, research on longitudinal changes in biomarkers is relatively limited. Studies have shown that the levels of plasma Aβ 42 /Aβ 40 , p-tau181 and glial fibrillary acidic...

After 70 years of age, language ability declines significantly, and more play and activity can delay it!

After 70 years of age, language ability declines significantly, and more play and activity can delay it!  70~74 years old is a turning point in the decline of language ability Playing more and more active can delay the decline of speech function Liu Chuqun, Professor of Jiangxi Normal University Decreased language fluency is an important speech performance of the elderly.  Studies have found that the age of 70 to 74 is an important turning point for the decline of verbal fluency, but a positive attitude and a healthy lifestyle can delay the decline of the elderly’s verbal fluency to a certain extent. After 70 years of age, language ability declines significantly Most of the elderly, especially the elderly, have these kinds of expressions: words that have no real meaning are repeated back and forth, lack of information to express, the words are inconsistent with what they think and form a verbal error, and the words cannot be remembered by the mouth (tip of tongue phenomenon), ...

Lack of Vitamin B12 during pregnancy, the child's cognitive impairment! Pregnant mothers must eat enough meat, eggs, and milk!

Lack of  Vitamin B12 during pregnancy, the child's cognitive impairment! Pregnant mothers must eat enough meat, eggs, and milk!  Lack of vitamin B 12 during pregnancy, the child's cognition is impaired Pregnant women have to eat enough meat, eggs, and milk Nutritional balance during pregnancy is very important. Once there is a lack of nutritional elements, it will easily affect the health of the fetus. Nowadays, most women preparing for pregnancy know that taking folic acid is essential for the healthy development of the fetus, but they don’t know much about vitamin B12. Recently, scientists from the University of Bristol in the UK published a study in the journal Nutrition Research that if the mother's intake of vitamin B 12 during pregnancy is insufficient, the child’s childhood language and mathematics development may be affected. Insufficient vitamin B 12 intake during pregnancy Affect children's language and math abilities Vitamin B 12 is also known as cobalamin, a...

What kind of children are prone to type 2 diabetes? These parents need to pay attention!

What kind of children are prone to type 2 diabetes? These parents need to pay attention!  Type 2 diabetes has become the main type of juvenile diabetes The 12-year-old Zhuang Zhuang (pseudonym) is taller and "stronger" than his peers. His height has already caught up with his mother (163cm), and his weight has reached 80 kg. The two generations of six people in the family are very caring for Zhuang Zhuang and satisfy any dietary requirements he puts forward. But recently the parents found that Zhuang Zhuang was a little faint, and they shouted thirsty to drink drinks all day long. Zhuang Zhuang's mother was diagnosed with gestational diabetes during pregnancy, and her grandmother also suffered from type 2 diabetes. My mother was a little worried about Zhuang Zhuang's recent performance, so she took Zhuang Zhuang to the hospital for a series of examinations. The diagnosis result was that Zhuang Zhuang had type 2 diabetes. The parents of Zhuang Zhuang are frowning at th...

Europe publishes guidelines for measuring blood pressure: Advocating blood pressure measurement at home, you have to know these things!

Europe publishes guidelines for measuring blood pressure: Advocating blood pressure measurement at home, you have to know these things!  Europe publishes guidelines for measuring hypertension.  Promote blood pressure measurement at home At present, blood pressure measurement mainly includes office blood pressure measurement, ambulatory blood pressure monitoring, and home blood pressure monitoring. Recently, the European Society of Hypertension released the "2021 Practice Guidelines for Blood Pressure Measurement in Clinics and Outside Clinics", which provides basic recommendations for blood pressure measurement in the clinics and outside the clinics. So, what should be paid attention to in home blood pressure monitoring? 1 Standard equipment should be used when measuring blood pressure The guidelines point out that blood pressure measurement equipment should use standard and validated blood pressure measurement equipment. Electronic sphygmomanometers verified in ordinary adul...

Breast cancer has become the world's most common cancer, and screening starts at the age of 40!

  Breast cancer has become the world's most common cancer, and screening starts at the age of 40!  Screening for breast cancer from the age of 40.  Recently, the International Agency for Research on Cancer of the World Health Organization released the latest global cancer burden data for 2020, which estimated the latest morbidity, mortality, and cancer development trends of 36 cancer types in 185 countries around the world.  Data show that in 2020, breast cancer will replace lung cancer as the world's most common cancer. On January 8, 2021, the Chinese Journal of Preventive Medicine "Chinese Journal of Cancer Prevention and Treatment" published online the Chinese Women's Breast Cancer Screening Standards (hereinafter referred to as "standards").  Regular screening and early intervention are important measures to effectively reduce the risk of breast cancer death. Why do we need to be screened? Screening can reduce breast cancer mortality According to the...